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The neurobiology of the masculinization of Four black man poster the brain is fairly well understood. Estradiol and testosterone, which is catalyzed by the enzyme 5α-reductase into dihydrotestosterone, act upon androgen receptors in the brain to masculinize it. If there are few androgen receptors (people with androgen insensitivity syndrome) or too much androgen (females with congenital adrenal hyperplasia), there can be physical and psychological effects. It has been suggested that both male and female heterosexuality are the results of this process. In these studies heterosexuality in females is linked to a lower amount of masculinization than is found in lesbian females, though when dealing with male heterosexuality there are results supporting both higher and lower degrees of masculinization than homosexual males.
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